Manufacturing and Dispensing of Suspension

1. Suspension containing diffusible solids:   • The drug is finely powdered with other ingredients.  • 3/4th of the vehicle is added to make cream.  • Addition of rest of vehicle.  • Volume is makeup.  • Suspension is l…

Types of Suspending Agents

1. Natural polysaccharides  (a) Acacia: Protective colloid and suspending agent used in a preparation containing resinous tincture that precipitates on the addition of water.  (b) Tragacanth: Better than acacia, used to suspe…

Applications of Suspension

1. Suspension is usually applicable for a drug that is insoluble or poorly soluble e.g. Prednisolone syrup.  2. To prevent degradation of the drug or to remove stability of the drug e.g. Oxytetracycline suspension.  3. To mas…

Advantages and Disadvantages of Suspensions

Suspensions are biphasic, heterogeneous systems in which finely divided insoluble solid particles (disperse phase) are dispersed or suspended in a vehicle (dispersion medium). • The diameter of disperse phase may range from 0.5…

Evaluation of Emulsion

Stability testing of emulsions involves determining stability at long-term storage conditions, accelerated storage conditions, and freezing and thawing conditions. Stress conditions are applied in order to speed up the stability …

Preservative used in Emulsion

Type Example Characteristic Acid and acid derivatives Benzoic acid  Sorbic acid  Propionic acid  Dehydroacetic acid  Antifungal Alcohols …

Theories of Emulsification

In the case of two immiscible liquids, the cohesive force between the molecules of each separate liquid exceeds the adhesive force between two liquids. This is manifested as interfacial energy or tension at the boundary between t…

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