Preparation of Mouthwash

Preparation of Mouthwash

These are aqueous solutions with a pleasant taste to clean, deodorize the buccal cavity.  Mouthwashes have refreshing, antiseptic and antibacterial activity and prevent Halitosis.


They may also contain alcohol, glycerin, synthetic sweeteners, surfactants, flavouring and colouring agents. They may be either acidic or basic in their reaction and in some instances are fairly effective in reducing bacterial concentration and odours in the mouth for short periods of time. 

For example: Compound sodium chloride mouthwash, Zinc chloride mouthwash, and Fluoride mouthwash. 

Storage: Keep in a cool and dry place, Dispense in clear, fluted bottles. 



• Not to be swallowed in large amounts 

• Pack in narrow mouth bottle 

Formula: Rx 

Zinc sulphate and zinc chloride mouthwash B.P.C. 

Zinc sulphate – 20 g 

Zinc chloride – 10 g 

Oilute hydrochloride acid – 10 ml 

Compound tartar zine solution – 10 ml 

Chloroform water to produce – 1000 ml 

The preparation may be made by dissolving Zinc sulphate and Zinc chloride in a small quantity of Chloroform solution. To this is added dilute hydrochloric acid and compound tartrazine solution and the final volume is made up with water.

Zinc sulphate and Zinc chloride included in the preparation acts as astringents.  Chloroform water acts as the flavouring agent and preservative while tartrazine serves as the colour. Zinc sulphate usually contains a small quantity of oxychloride which may make the solution turbid. This however disappears on the addition of dilute hydrochloric acid.

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