Packaging of Suspensions

Packaging of Suspensions

Pharmaceutical suspensions for oral use are generally packed in wide-mouth containers having adequate space above the liquid to ensure proper mixing. 

Parenteral suspensions are packed in either glass ampoules or vials.


Ideal Requirements of Packaging Material 

• It should be inert. 

• It should effectively preserve the product from light, air, and other contamination through shelf life. 

• It should be cheap. 

• It should effectively deliver the product without any difficulty.

Materials Used For Packaging 

Generally, glass and various grades of plastics are used in the packaging of suspension. 


Generally, soda lime and borosilicate glass are used in the preparation of non-sterile suspensions.  Amber glass does not allow UV light to pass through. Amber characteristics can be developed in the glass by the addition of various types of additives. 

Disadvantages of Glass Materials 

• They are fragile. 

• They are very heavy as compared to plastic so handling and transport are difficult. 

• The most important disadvantage of glass is that glass constituents get extracted into the product. 


Due to the negative aspects of glass, plastic material significantly use of plastic as packaging material for sterile as well as non-sterile pharmaceutical suspension increased. 

Advantages of Plastic Material 

Materials used: Polyethylene, Poly Vinylene Chloride, Polystyrene, Polycarbonate etc. 

Closure and Liners

With the exception of ampoules, all containers required elastomeric closure. 

Factors affecting in selecting closure 

• Compatibility with product 

• Seal integrity 

• It should be stable throughout the shelf life 

Factors affecting in selecting a liner 

• Chemical resistance 

• Appearance 

• Gas and vapour transmission 

• Removal torque 

• Heat resistance 

• Shelf life 

• Economical factors

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